This collection of papers contains the results of research carried out by the participants of the «International Project FOLPSEC ? 295050 within the 7th EU Framework Programme FP7-PEOPLE-2011 IRSES» «Functioning of the Local Production Systems in the Conditions of Economic Crisis (Comparative Analysis and Benchmarking for the EU and Beyond)». These papers study the following problems: general approaches to forecasting the development of local production systems (LPS), the possibilities of LPS-based clusters formation, methodological approaches to the creation of LPS, strategic planning of regional development, innovativeness of clusters, program approach to environmental management, local production system management, governance of local production systems in Bulgaria, Poland, Slovakia, Ukraine and Russia.